Ju Han Kim

Ju Han Kim
Ju Han Kim

Seoul National Univ. College of Medicine, Seoul  / M.D.
Seoul National Univ. College of Medicine, Seoul  / M.S.
Seoul National Univ. College of Medicine, Seoul  / Ph.D.
M.I.T, Cambridge,  / MA M.Sc.

 

♦ Personal Statement

Ju Han Kim, M.D., Ph.D., M.S. is a Professor and Founding Chairs of the Division of Biomedical Informatics, Seoul National University College of Medicine and of Interdisciplinary Program of Medical Informatics of Seoul National University Graduate School. He established Systems Biomedical Informatics National Core Research Center at Seoul National University in 2010.
Ju Han Kim obtained his M.D. and Ph.D. degrees from Seoul National University in Seoul, South Korea and completed his residency training in Neuro-psychiatry at Seoul National University Hospital in 1996. During his residency program in 1995, Ju Han Kim has developed a psychiatric electronic medical record system, PsyBase, which is cited as the first real practice use of electronic medical record in Korea.Ju Han Kim’s carrier has been focused on the state-of-the-art information technology and its impact on and utility of clinical medicine and biomedical research.
Dr. Kim joined Dr. Charles Safran’s Center for Clinical Computing at Boston’s BIDMC in 1997. One of his project, SeniorMed, is considered as a very early version of PHR and consumer engagement based on standard HL-7/XML messaging technology to facilitate direct physician-patient communication. Getting more interested in the rapidly developing fieldof bioinformatics, Dr. Kim joined the Children’s Hospital Informatics Program at BostonsChildrens Hospital, Harvard Medical School as an Instructor of Medicine in Biomedical Informatics. He obtained anadditional M.S. degree in Biomedical Informatics at MIT and became an assistant professor of Harvard Medical School. Dr. Kim returned back to Seoul National University College of Medicine and founded Div. of Biomedical Informatics. He has developed a series of prominent bioinformatics softwares and algorithms as well as integrative models and databases.
His research focuses on integration of clinical and genomic data. His Health Avatar CCR+ is cited as the first working PHR in Korea. DNet is a nation-wide network of (institution-centered) EMR, (physician-centered iPad) DialysisNet, and (patient-centered smartphone PHR) Avatar Beans connects 14 teaching hospitals, physicians, and their patients. KidsNet is a sister network for childhood leukemia, sequencing personal genomes to protecting them from severe adverse drug reactions to realize precision medicine. His leadership at the intersection of medical informatics and bioinformatics can be described by his prominent effort in founding a renowned international conference, the Translational Bioinformatics Conference. The 7th TBC 2017 will be held in Los Angeles, CA, this year chaired by Professor Marylyn D. Ritchie at Geisinger.

 

♦ Positions and Honors
Positions and Employment
2000(Mar.)-2001(Apr.)  Instructor, Biomedical Informatics, The Children’s Hospital, Harvard Medical School, Boston, MA 02115, U.S.A.
2001(May)-2002(Aug.)  Assistant Professor, Biomedical Informatics, The Children’s Hospital, Harvard Medical School, Boston, MA 02115, U.S.A.
2001(Sep.)-2005(Aug.)  Assistant Professor, Biomedical Informatics, Seoul National University College of Medicine, Seoul 110799, Korea
2005(Sep.)-2009(Aug.)  Associate Professor, Biomedical Informatics, Seoul National University College of Medicine, Seoul 110799, Korea
2009(Sep.)to present      Professor and Founding Chair, Div. of Biomedical Informatics, Seoul National University College of Medicine, Seoul 110799, Korea
2010(Mar.)to present     Professor and Founding Chair, Interdisciplinary Program of Medical Informatics, Seoul National University Graduate School, Seoul 110799, Korea

 

♦ Honors
1996(Sep.)  MSD (Merk Sharp & Dohme) Korea Scholarship for training clinical trial expert, Clinical Trial Center, Seoul National University Hospital
2003(Sep.)   Best Paper Award, Korean Society of Medical Informatics
2003(Dec.)  Best Alumni Award, Seoul National University Hospital Neuropsychiatry
2005(Apr.)  “Best Paper Award”, Korean Federation of Scienceand TechnologySocieties
2005(Apr.)  “SCI Impact Factor Award”, Seoul National University Hospital
2006(Sep.)  “OnBIT prize”, Korean Society of Bioinformatics
2010(Apr.)  Best Lecturer Award, Seoul National Univ. College of Medicine
2012(Feb.)  Numerous Paper Award, Korean Society of Genomics
2012(Dec. 25)  CIGIF 2012 GRAD PRIX AWARD TELEMEDICAL STETHOSCOPE
2012(Dec. 25)  Gold Prize, CIGIF 2012 (2012 Korea Cyber International Geinus Fair), TELEMEDICAL STETHOSCOPE
2012(Dec.)   WIPO Award for Best Inventor, World Intellectual Property Organization
2014(Dec.)  Silver Prize SIIF 2014 “Composite Medical Device”

 

♦ Contributions to Science

1. Medical Informatics:
Ju Han Kim, M.D., Ph.D., have developed a psychiatric electronic medical record system, PsyBase, in 1995which is cited as the first real practice use of EMR in Korea.Ju Han Kim’s carrier has been focused on the state-of-the-art information technology and its impact on and utility of clinical medicine and biomedical research.In 1997 he joined Drs. Charles Safran and Warner Slack who have developed prominent hospital information system and interactive computing in Boston’s Beth Israel Deaconess Medical Center. One of Ju Han Kim’s fellowship project, SeniorMed, is designed to provide chronically ill elderly patients with their prescription information stored in legacy hospital information system augmented with modern medication databases with secure internet connectivity and standard HL-7/XML messaging technology for the purpose of facilitating direct physician-patient communication and enhancing the quality of care. The current buzz word, PHR or Personal Health Record, can be regarded as an evolved form of the ‘disclosure’ things. His research focuses on integration of clinical and genomic data. His Health Avatar CCR+ is cited as the first working PHR in Korea. DNet is a nation-wide network of (institution-centered) EMR, (physician-centered iPad) DialysisNet, and (patient-centered smartphone PHR) Avatar Beans connects 14 teaching hospitals, physicians, and their patients. KidsNet is a sister network for childhood leukemia, sequencing personal genomes to protecting them from severe adverse drug reactions to realize precision medicine.

  • Standard-based Comprehensive Detection of Adverse Drug Reaction Signals from  Nursing Statements and Laboratory Results in Electronic Health Records. Suehyun Lee, Jiyeob Choi, Hun-Sung Kim, Grace Juyun Kim, Kye Hwa Lee, Chan Hee Park, Jongsoo Han, Dukyong Yoon, Man Young Park, Raewoong Park, Ju Han Kim JAMIA 2017 Mar 13 MELLO: Medical Lifelog Ontology for data terms from self-tracking and life-log devices.  HyeHyeon Kim, Soo Youn Lee, Su YounBaik, and Ju Han Kim   International Journal of Medical Informatics 2015 Dec;84(12):1099-100
  • Bi-directional measure of semantic similarity for optimizing biological and clinical analyses.Sang Jay Bien§, Chan Hee Park§, HaeJin Shim, Woongcheol Yang, Jihun Kim, Ju Han Kim JAMIA 2012;19(5):765-774
  • Using mobile phones in healthcare management for the elderly. Hun-Sung Kim, Kye Hwa Lee, Hyunah Kim, Ju Han Kim Maturitas 2014;79:381-388
  • Future prospects of health management system using cellular phone. Kim, Hun-Sung; Hwang, Yunji, Lee, Jae-Ho; Oh, Hye young; Kang, Hyoseung; Kim, Yi-Jun; Kwon, Hyeon Yoon; Kim, Hyunah; Park, Rae Woong; Ju Han Kim Telemedicine and e-Health 2014 Jun;20(6):544-55

2. Translational Bioinformatics
Dr. Ju Han Kim founded the first biomedical informatics lab. in Korea, SNUBI (Seoul National University Biomedical Informatics), which has developed a series of prominent bioinformatics softwares and algorithms like ArrayXPath, deCoxS, BioLattice, ChromoViz, DIB-C and GOChase as well as integrative models and databases like BioEMR, TMA-OM and GRIP. His research focuses on integration of clinical and genomic data.

  • Knowledge Boosting: A graph-based integration with multi-omics data and genomic knowledge for cancer clinical outcome prediction. Dokyoon Kim, Je-Gun Joung, Kyung-Ah Sohn, Hyunjung Shin, Marylyn D. Ritchie, Ju Han Kim JAMIA 2015 Jan;22(1):109-120
  • Extracting of Coordinated Patterns of DNA Methylation and Gene Expression in Ovarian Cancer. Je-Gun Jeong, Dokyoon Kim, Kyung Hwa Kim, Ju Han Kim JAMIA 2013 Jul-Aug;20(4):637-42  doi:10.1136/amiajnl-2012-001571
  • hiHMM: Bayesian non-parametric joint inference of chromatin state maps. Kyung-Ah Sohn, Joshua W. K. Ho, DjordjeDjordjevic, Peter J. Park* and Ju Han Kim* Bioinformatics 2015;31(13):2066-2074
  • Comparative analysis of metazoan chromatin architecture. Joshua Ho, Youngsook Jung, Tao Liu, BurakAlver, Soohyun Lee, Kohta Ikegami, Kyung-Ah Sohn, et al. Nature 2014 August 28;512(7515):449–452
  • Yin and Yang of disease genes and death genes between reciprocally scale free biological networks. Hyun Wook Han§, Jung Hun, Ohn§, Jisook Moon*, Ju Han Kim*§eqully contributed Nucleic Acid Research 2013 Nov 1;41(20):9209-9217
  • Post-translational control of T-cell development by the ESCRT protein CHMP5. Stanley Adoro , Kwang Hwan Park , Sarah Bettigole, Raphael Lis, Hee Rae Shin, HeewonSeo, Ju Han Kim, Klaus-Peter Knobeloch, Jae-Hyuck Shim, Laurie Glimcher. Nature Immunology  2017

 

3. Pharmacogeomics and Drug Safety

  • Genome Sequence Variability Predicts Drug Precautions and Withdrawals from the Market. Kye Hwa Lee, Su YounBaik, Soo Youn Lee, Chan Hee Park, Paul J. Park, Ju Han Kim PLoS One 2016 Sep 30;11(9):e0162135
  • Role of preemptive genotyping in preventing serious adverse drug events in South Korean patients. Grace Juyun Kim, Soo Youn Lee, Ji Hye Park, Brian Y. Ryu, Ju Han Kim  Drug Safety 2017 Jan;40(1):65-80
  • Statin-related aminotransferase elevation according to baseline aminotransferases level in real practice in Korea. Hun-Sung Kim, S. H. Lee, H. Kim, S.-H. Lee, J. H. Cho, H. Lee, H. W. Yim, S.-H. Kim, I.-Y. Choi, K.-H. Yoon, Ju Han Kim Journal of Clinical Pharmacy and Therapeutics 2016 Jun;41(3):266-272

 

♦ Additional Information: Research Support and/or Scholastic Performance

  • Precision Medicine and Clinical Evaluation Technologies for Childhood Rare Cancers (2016~2019), USD$ 3M grant (MDFS2016-22774) by the Ministry of Food and Drug Safety, Korea
  • PharmSafe and PharmCoach (2016~2018), USD$500K grant (HI16C11280000) by the Korean Health Technology R&D Project, Ministry of Health and Welfare, Korea
  • BITEC (Biomedical Informatics Training and Education Center) (2013~2018), USD 2.1M grant (HI13C2164) of the Korean Health Technology R&D Project, Ministry of Health and Welfare, Korea
  •  K-CDM and K-Sentinel Initiative (2017), UDS$7K fund (MFDS2017-388) by Ministry of Food and Drug Safety, Korea
  • The Health Avatar Project: Systems Biomedical Informatics Research Center (2010~2017), USD$ 11M supported by the National Research Foundation of Korea(NRF) grant funded by the Korea government (MSIP) (2012-0000994)

 

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